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Some causes of constipation can include: Dietary changes The use of antacids that contain calcium or aluminum IBS Inactivity Lack of water or fiber Pregnancy Overuse of laxatives Some medications, such as antidepressants and iron supplements Hypothyroidism Stress Gastroenteritis Gastroenteritis is a condition where the stomach and intestines become irritated and inflamed, usually as a result of a bacterial or viral infection